Wednesday, November 5, 2008

HoPingKong-isms Redux

1. "This cup is housing water"...referring to the WaterhouseFriderichsen Syndrome: bilateral adrenal hemorrhage classically occurring with disseminated Neisseria meningitidis infection, but also with sepsis from any etiology.


2. "You're a big hit here"...referring to Heparin-Induced Thrombocytopenia. The more serious form of this, Type II 'HIT', is an immune mediated hypercoaguable disorder that presents roughly 3-10 days after exposure to the drug. Heparin should be stopped immediately, and patients will require anticoagulation with a non-heparin like compound, such as Lepirudin or Argatroban. Here is a good review.

3. "Your name is Adam, right? I'd change it to Stoke"...referring to Stokes-Adams attacks, aka Cardiac Syncope. Named after Robert Adams and William Stokes.

4. "No man is an island"...referring to the pancreatic Islets of Langerhans. These are clusters of cells which include Alpha cells (glucagon), Beta cells (insulin), and Delta cells (somatostatin). The picture above is a recent British Medical Journal cover showing the Islets of Langerhans....or earth from from outer space.

5. "This is a big question...an obese question"...referring to fat embolism. This is an uncommon condition which can occur after pelvic or long-bone fractures. The symptom triad includes hypoxemia, neurologic changes, and a petichial rash of the face, upper thorax and axilla. Here is a good article

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