Today we discussed an unfortunate patient with multisystem disease, a positive ANA (as depicted here) and a new diagnosis of SLE.SLE appears on the differential in many medical conditions due to the multiple organs it can involve (and the multiple manifestations required for diagnosis).
The diagnositic criteria for SLE can be found at this site.
A pathophysiologic review, with a table of the classic rhematologic antibody assays is published in NEJM here.
Have a great weekend!
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